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Fig. 5 The ventralizing effect of Cvl2-N depends on Bmp2b, but is partly independent of Chordin. (A-F) krox20 staining. (A) Wild type, (B) wild type injected with cvl2-N mRNA, (C) bmp2b morphant, (D) bmp2b morphant injected with cvl2-N mRNA, (E) chd mRNA injected embryo and (F) chd plus cvl-N mRNA injected embryo. cvl2-N mRNA can rescue dorsalization caused by chd mRNA but not by bmp2b MO. (G,H) Lateral views of 32 hpf embryos. The ventralization of (G) chd MO injected embryos is enhanced by co-injection of (H) cvl2-N mRNA.
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