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Fig. 4 zfBLP1 overexpression promotes programmed cell death in the hyperplastic liver. A,B: Detection of apoptotic cells in normal liver (A) of 5 days postfertilization (dpf) wild-type zebrafish larvae and hyperplastic liver (B) of 5 dpf zebrafish larvae overexpressing zfBLP1 by the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling (TUNEL) assay. C,D: Comparison of the normal (C) and hyperplastic liver (D) of 5 dpf zebrafish larvae revealed an increased level of cell death in the expanded lobe of the hyperplastic liver where zfBLP1 is overexpressed.
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