Gene
cd74b
- ID
- ZDB-GENE-990910-10
- Name
- CD74 molecule, major histocompatibility complex, class II invariant chain b
- Symbol
- cd74b Nomenclature History
- Previous Names
-
- cd74
- Iclp-2
- iclp2
- zgc:123161
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable MHC class II protein binding activity; cytokine receptor activity; and macrophage migration inhibitory factor binding activity. Acts upstream of or within inner ear development and neuromast development. Predicted to be located in membrane. Predicted to be active in cell surface and cytoplasm. Is expressed in inner ear and otic vesicle. Orthologous to human CD74 (CD74 molecule).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000716 | Thyroglobulin type-1 |
| Domain | IPR015386 | MHC class II-associated invariant chain/CLIP, MHC II-interacting |
| Family | IPR043530 | HLA class II histocompatibility antigen, gamma subunit |
| Family | IPR052001 | MHC Class II Gamma Chain/Thyroglobulin |
| Homologous_superfamily | IPR036857 | Thyroglobulin type-1 superfamily |
Domain Details Per Protein
| Protein | Length | HLA class II histocompatibility antigen, gamma subunit | MHC class II-associated invariant chain/CLIP, MHC II-interacting | MHC Class II Gamma Chain/Thyroglobulin | Thyroglobulin type-1 | Thyroglobulin type-1 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9PVD9
|
198 |
Interactions and Pathways
No data available
Plasmids
No data available