Gene
sema4e
- ID
- ZDB-GENE-990715-7
- Name
- semaphorin 4e
- Symbol
- sema4e Nomenclature History
- Previous Names
-
- sema7
- semaZ7
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension involved in axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in central nervous system; pectoral fin bud; and pharyngeal arch. Orthologous to human SEMA4D (semaphorin 4D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Halloran et al., 1998
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001627 | Sema domain |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR016201 | PSI domain |
| Family | IPR027231 | Semaphorin |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR036352 | Sema domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
| Protein | Length | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Plexin repeat | PSI domain | Sema domain | Sema domain superfamily | Semaphorin | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9YHX4
|
766 | ||||||||||
|
UniProtKB:F1QNC4
|
766 | ||||||||||
|
UniProtKB:A4JYS3
|
766 | ||||||||||
|
UniProtKB:Q1MT68
|
766 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sema4e-201
(1)
|
Ensembl | 2,303 nt | ||
| mRNA |
sema4e-202
(1)
|
Ensembl | 2,619 nt | ||
| mRNA |
sema4e-203
(1)
|
Ensembl | 2,918 nt |
Interactions and Pathways
No data available
Plasmids
No data available