Gene
dkk1b
- ID
- ZDB-GENE-990708-5
- Name
- dickkopf WNT signaling pathway inhibitor 1b
- Symbol
- dkk1b Nomenclature History
- Previous Names
-
- dkk1
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable co-receptor binding activity and receptor antagonist activity. Acts upstream of or within several processes, including hepaticobiliary system development; posterior lateral line neuromast development; and sensory epithelium regeneration. Located in cytoplasm and extracellular region. Is expressed in several structures, including embryonic structure; median fin fold; mesoderm; pharyngeal arch; and sensory system. Human ortholog(s) of this gene implicated in anodontia. Orthologous to human DKK1 (dickkopf WNT signaling pathway inhibitor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 66 figures from 54 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006796 | Dickkopf, N-terminal cysteine-rich |
| Domain | IPR047304 | Dickkopf-related protein 1, second cysteine-rich domain |
| Domain | IPR048499 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 |
| Domain | IPR048500 | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 |
| Family | IPR039863 | Dickkopf related protein 1-4 |
Domain Details Per Protein
| Protein | Length | Dickkopf, N-terminal cysteine-rich | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 | Dickkopf related protein 1-4 | Dickkopf-related protein 1, second cysteine-rich domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9PWH3
|
240 | |||||
|
UniProtKB:Q9W6D9
|
241 |
Interactions and Pathways
Plasmids
No data available