Gene
ephb3a
- ID
- ZDB-GENE-990415-60
- Name
- eph receptor B3a
- Symbol
- ephb3a Nomenclature History
- Previous Names
-
- ek3
- epha3a
- rtk3 (1)
- zek3
- fc62d03
- wu:fc62d03
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable ephrin receptor activity. Predicted to be involved in several processes, including ephrin receptor signaling pathway; neuron projection development; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within nervous system development; protein phosphorylation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in dendrite and membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior neural keel; central nervous system; hypoblast; immature eye; and mesoderm. Orthologous to human EPHB3 (EPH receptor B3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144764 (9 images)
- eu875 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008266 | Tyrosine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Conserved_site | IPR001426 | Tyrosine-protein kinase, receptor class V, conserved site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001090 | Ephrin receptor ligand binding domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001660 | Sterile alpha motif domain |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
| Domain | IPR027936 | Ephrin receptor, transmembrane domain |
| Domain | IPR034245 | Ephrin type-B receptor 3, ligand binding domain |
| Family | IPR016257 | Ephrin receptor type-A /type-B |
| Family | IPR050449 | Ephrin receptor tyrosine kinases |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Length | Ephrin receptor ligand binding domain | Ephrin receptor, transmembrane domain | Ephrin receptor type-A /type-B | Ephrin receptor tyrosine kinases | Ephrin type-B receptor 3, ligand binding domain | Fibronectin type III | Fibronectin type III superfamily | Galactose-binding-like domain superfamily | Growth factor receptor cysteine-rich domain superfamily | Immunoglobulin-like fold | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | Sterile alpha motif domain | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, receptor class V, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z0S5
|
961 | ||||||||||||||||||
|
UniProtKB:A0A8M3AP95
|
659 | ||||||||||||||||||
|
UniProtKB:O13147
|
500 | ||||||||||||||||||
|
UniProtKB:Q90ZN8
|
923 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ephb3a-201
(1)
|
Ensembl | 4,322 nt |
Interactions and Pathways
No data available
Plasmids
No data available