Gene
foxn4
- ID
- ZDB-GENE-990415-277
- Name
- forkhead box N4
- Symbol
- foxn4 Nomenclature History
- Previous Names
-
- whn
- sli
- slipjig
- whna (1)
- winged helix nude
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in heart development; positive regulation of transcription, DNA-templated; and regulation of heart contraction. Predicted to localize to nucleus. Is expressed in several structures, including forebrain neural keel; nervous system; optic vesicle; pericardial region; and presumptive neural retina. Orthologous to human FOXN4 (forkhead box N4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR030456 | Fork head domain conserved site 2 |
| Domain | IPR001766 | Fork head domain |
| Family | IPR049624 | Forkhead box protein N1/4 |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Forkhead box protein N1/4 | Fork head domain | Fork head domain conserved site 2 | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A2BGM5
|
550 | |||||
|
UniProtKB:A0A8M2BC99
|
549 |
Interactions and Pathways
No data available
Plasmids