Gene
tpma
- ID
- ZDB-GENE-990415-269
- Name
- alpha-tropomyosin
- Symbol
- tpma Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in myeloid cell development. Predicted to localize to actin filament. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Y; familial hypertrophic cardiomyopathy; hypertrophic cardiomyopathy 3; and nemaline myopathy 1. Is expressed in adaxial cell; male organism; musculature system; pericardial region; and somite. Orthologous to several human genes including TPM1 (tropomyosin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 37 figures from 26 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77897 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Gieger et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Family | IPR000533 | Tropomyosin |
Domain Details Per Protein
Protein | Length | Tropomyosin |
---|---|---|
UniProtKB:P13104
|
284 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA | tpma-001 (1) | Havana | 1618 nt | |
mRNA | tpma-002 (1) | Havana | 1407 nt | |
mRNA |
tpma-201
(1)
|
Havana | 812 nt | |
mRNA |
tpma-202
(1)
|
Havana | 3089 nt | |
mRNA |
tpma-203
(1)
|
Havana | 529 nt | |
mRNA |
tpma-204
(1)
|
Havana | 721 nt | |
mRNA |
tpma-205
(1)
|
Havana | 487 nt | |
mRNA |
tpma-206
(1)
|
Havana | 402 nt | |
mRNA |
tpma-207
(1)
|
Havana | 631 nt | |
mRNA |
tpma-208
(1)
|
Havana | 751 nt | |
mRNA |
tpma-209
(1)
|
Havana | 753 nt | |
mRNA |
tpma-210
(1)
|
Havana | 639 nt |
Interactions and Pathways
No data available
Plasmids
No data available