Gene
tap2c
- ID
- ZDB-GENE-990415-260
- Name
- transporter associated with antigen processing, subunit type c
- Symbol
- tap2c Nomenclature History
- Previous Names
-
- tap2 (1)
- abcb3
- si:dz179b20.3
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable ABC-type peptide transporter activity and ATP binding activity. Acts upstream of or within response to methylmercury. Predicted to be located in lysosomal membrane. Is expressed in brain; liver; and musculature system. Human ortholog(s) of this gene implicated in several diseases, including MHC class I deficiency; aspirin-induced respiratory disease; autoimmune disease (multiple); cervical cancer (multiple); and systemic scleroderma (multiple). Orthologous to human TAP2 (transporter 2, ATP binding cassette subfamily B member).
- Genome Resources
-
- Alliance (1)
- Gene:30695 (1)
- VEGA:OTTDARG00000001710 (1)
- Note
-
No gene match in Ensembl GRCz11.
- Comparative Information
-
- All Expression Data
- 3 figures from Gonzalez et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| MHC class I deficiency 2 | 620813 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance