Gene
rrm2
- ID
- ZDB-GENE-990415-25
- Name
- ribonucleotide reductase M2 polypeptide
- Symbol
- rrm2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to have ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in several structures, including nervous system; pectoral fin musculature; pharyngeal arch 3-7 skeleton; proliferative region; and tail bud. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb111 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR030475 | Ribonucleotide reductase small subunit, acitve site |
Family | IPR000358 | Ribonucleotide reductase small subunit family |
Family | IPR033909 | Ribonucleotide reductase small subunit |
Homologous_superfamily | IPR009078 | Ferritin-like superfamily |
Homologous_superfamily | IPR012348 | Ribonucleotide reductase-like |
Domain Details Per Protein
Protein | Length | Ferritin-like superfamily | Ribonucleotide reductase-like | Ribonucleotide reductase small subunit | Ribonucleotide reductase small subunit, acitve site | Ribonucleotide reductase small subunit family |
---|---|---|---|---|---|---|
UniProtKB:P79733
|
386 | |||||
UniProtKB:G3G7U0
|
386 |
Interactions and Pathways
No data available
Plasmids
No data available