Gene
lhx5
- ID
- ZDB-GENE-980526-484
- Name
- LIM homeobox 5
- Symbol
- lhx5 Nomenclature History
- Previous Names
-
- lim5
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in eye development and forebrain development. Predicted to localize to nucleus. Is expressed in CiA; forebrain; hindbrain; neural keel; and presumptive ectoderm. Orthologous to human LHX5 (LIM homeobox 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 30 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR001781 | Zinc finger, LIM-type |
| Domain | IPR049618 | Lhx1/5, LIM domain 1 |
| Domain | IPR049619 | Lhx1/5, LIM domain 2 |
| Family | IPR050453 | LIM/homeobox transcription factors |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Lhx1/5, LIM domain 1 | Lhx1/5, LIM domain 2 | LIM/homeobox transcription factors | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:P52889
|
399 |
Interactions and Pathways
No data available
Plasmids