Gene
wnt2
- ID
- ZDB-GENE-980526-416
- Name
- wingless-type MMTV integration site family member 2
- Symbol
- wnt2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within hepatocyte proliferation and swim bladder development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including nervous system; optic cup; optic vesicle; otic vesicle; and swim bladder bud. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system cancer. Orthologous to human WNT2 (Wnt family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65730 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Poulain et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt-2 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q92048
|
350 |
Interactions and Pathways
No data available
Plasmids
No data available