Gene
otx2a
- ID
- ZDB-GENE-980526-27
- Name
- orthodenticle homeobox 2a
- Symbol
- otx2a Nomenclature History
- Previous Names
-
- otx1a
- otx1l
- otx3
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within brain development and retinal pigment epithelium development. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural keel; axis; brain; immature eye; and neural plate. Orthologous to human OTX1 (orthodenticle homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu812 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Transcription factor Otx | Transcription factor Otx, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:Q90267
|
338 |
Interactions and Pathways
No data available
Plasmids
No data available