Gene
otx2a
- ID
- ZDB-GENE-980526-27
- Name
- orthodenticle homeobox 2a
- Symbol
- otx2a Nomenclature History
- Previous Names
-
- otx1a
- otx1l
- otx3
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in brain development and retinal pigment epithelium development. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; axis; brain; immature eye; and neural plate. Orthologous to human OTX1 (orthodenticle homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu812 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Transcription factor Otx | Transcription factor Otx, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:Q90267
|
338 |
Interactions and Pathways
No data available
Plasmids
No data available