Gene

pou3f3a

ID

ZDB-GENE-980526-220

Name

POU class 3 homeobox 3a

Symbol

pou3f3a Nomenclature History

Previous Names

pou12
brn1.1
wu:fc33a11
zp12

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in central nervous system; neural tube; neurons; pharyngeal arch; and pronephric duct. Orthologous to human POU3F3 (POU class 3 homeobox 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:76858 (24 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pou3f3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Snijders Blok-Fisher syndrome	618604

Associated With pou3f3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR000327	POU-specific domain
Domain	IPR001356	Homeodomain
Domain	IPR013847	POU domain
Family	IPR016362	POU-domain transcription factor, class 3
Family	IPR050255	POU domain transcription factor
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR010982	Lambda repressor-like, DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Homedomain-like superfamily	Homeobox, conserved site	Homeodomain	Lambda repressor-like, DNA-binding domain superfamily	POU domain	POU domain transcription factor	POU-domain transcription factor, class 3	POU-specific domain
UniProtKB:P56224 InterPro	438

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pou3f3a-201 (1) Ensembl	Ensembl	2,747 nt	Select Tool
mRNA	pou3f3a-202 (1) Ensembl	Ensembl	2,891 nt	Select Tool
mRNA	pou3f3a-203 (1) Ensembl	Ensembl	2,959 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations