Gene

pou3f3a

ID

ZDB-GENE-980526-220

Name

POU class 3 homeobox 3a

Symbol

pou3f3a Nomenclature History

Previous Names

pou12
brn1.1
wu:fc33a11
zp12

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in central nervous system; neural tube; neurons; pharyngeal arch; and pronephric duct. Orthologous to human POU3F3 (POU class 3 homeobox 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:76858 (24 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pou3f3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Snijders Blok-Fisher syndrome	618604

Associated With pou3f3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR000327	POU-specific domain
Domain	IPR001356	Homeodomain
Domain	IPR013847	POU domain
Family	IPR016362	POU-domain transcription factor, class 3
Family	IPR050255	POU domain transcription factor
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR010982	Lambda repressor-like, DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Homedomain-like superfamily	Homeobox, conserved site	Homeodomain	Lambda repressor-like, DNA-binding domain superfamily	POU domain	POU domain transcription factor	POU-domain transcription factor, class 3	POU-specific domain
UniProtKB:P56224 InterPro	438

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pou3f3a-201 (1) Ensembl	Ensembl	2,747 nt	Select Tool ZFIN BLAST
mRNA	pou3f3a-202 (1) Ensembl	Ensembl	2,891 nt	Select Tool ZFIN BLAST
mRNA	pou3f3a-203 (1) Ensembl	Ensembl	2,959 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations