Gene

tdrd7b

ID

ZDB-GENE-150109-14

Name

tudor domain containing 7 b

Symbol

tdrd7b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable mRNA binding activity. Predicted to be involved in lens development in camera-type eye; post-transcriptional regulation of gene expression; and spermatogenesis. Predicted to act upstream of or within cell differentiation. Predicted to be located in ribonucleoprotein granule. Human ortholog(s) of this gene implicated in cataract 36. Orthologous to human TDRD7 (tudor domain containing 7).

Genome Resources

Note

corresponds to ENSDARG00000077523

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tdrd7b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
cataract 36	Alliance	Cataract 36	613887

Associated With tdrd7b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002999	Tudor domain
Domain	IPR025605	OST-HTH/LOTUS domain
Domain	IPR037978	TDRD7, third LOTUS domain
Domain	IPR047448	TDRD7, second Tudor domain
Domain	IPR047449	TDRD7, third Tudor domain
Family	IPR050621	Tudor domain-containing
Homologous_superfamily	IPR035437	SNase-like, OB-fold superfamily
Homologous_superfamily	IPR041966	LOTUS-like domain

Domain Details Per Protein

Protein	Length	LOTUS-like domain	OST-HTH/LOTUS domain	SNase-like, OB-fold superfamily	TDRD7, second Tudor domain	TDRD7, third LOTUS domain	TDRD7, third Tudor domain	Tudor domain	Tudor domain-containing
UniProtKB:E7FDW8 InterPro
UniProtKB:A0A8M1QHU1 InterPro	937

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	tdrd7b-201 (1) Ensembl	Ensembl		4,588 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations