Gene

capn15

ID

ZDB-GENE-140106-70

Name

calpain 15

Symbol

capn15 Nomenclature History

Previous Names

zmp:0000001110 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have calcium-dependent cysteine-type endopeptidase activity and metal ion binding activity. Predicted to be involved in proteolysis. Orthologous to human CAPN15 (calpain 15).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Ma et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With capn15 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Oculogastrointestinal neurodevelopmental syndrome	619318

Associated With capn15 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR000169	Cysteine peptidase, cysteine active site
Domain	IPR001300	Peptidase C2, calpain, catalytic domain
Domain	IPR001876	Zinc finger, RanBP2-type
Family	IPR022684	Peptidase C2, calpain family
Homologous_superfamily	IPR036443	Zinc finger, RanBP2-type superfamily
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily

Domain Details Per Protein

Protein	Length	Cysteine peptidase, cysteine active site	Papain-like cysteine peptidase superfamily	Peptidase C2, calpain, catalytic domain	Peptidase C2, calpain family	Zinc finger, RanBP2-type	Zinc finger, RanBP2-type superfamily
UniProtKB:E7FAX5 InterPro	1122
UniProtKB:A0A8M2BLF5 InterPro	1153

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	capn15-201 (1) Ensembl	Ensembl		3,369 nt	Select Tool ZFIN BLAST
mRNA	capn15-202 (1) Ensembl	Ensembl		3,462 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations