Gene
nfat5b
- ID
- ZDB-GENE-140106-7
- Name
- nuclear factor of activated T cells 5b
- Symbol
- nfat5b Nomenclature History
- Previous Names
-
- zmp:0000001047 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in calcineurin-NFAT signaling cascade; cytokine production; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytosol and nuclear transcription factor complex. Orthologous to human NFAT5 (nuclear factor of activated T cells 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Charlton-Perkins et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002909 | IPT domain |
| Domain | IPR011539 | Rel homology domain, DNA-binding domain |
| Domain | IPR015646 | Nuclear factor of activated T-cells 5, Rel homology domain, DNA-binding domain |
| Domain | IPR032397 | Rel homology dimerisation domain |
| Family | IPR008366 | Nuclear factor of activated T cells (NFAT) |
| Homologous_superfamily | IPR008967 | p53-like transcription factor, DNA-binding domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR037059 | Rel homology domain (RHD), DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Nuclear factor of activated T-cells 5, Rel homology domain, DNA-binding domain | Nuclear factor of activated T cells (NFAT) | p53-like transcription factor, DNA-binding domain superfamily | Rel homology dimerisation domain | Rel homology domain, DNA-binding domain | Rel homology domain (RHD), DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IIR4
|
1257 | |||||||||
|
UniProtKB:A0A8M9Q2Y6
|
1261 | |||||||||
|
UniProtKB:A0A8M9QI62
|
1188 | |||||||||
|
UniProtKB:A0A8M9Q932
|
1261 | |||||||||
|
UniProtKB:A0A8M3BBF4
|
1258 | |||||||||
|
UniProtKB:A0A8M9PQA8
|
1262 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nfat5b-201
(1)
|
Ensembl | 1,694 nt | ||
| mRNA |
nfat5b-202
(1)
|
Ensembl | 3,774 nt | ||
| mRNA |
nfat5b-203
(1)
|
Ensembl | 3,180 nt |
Interactions and Pathways
No data available
Plasmids
No data available