Gene

adgrg2a

ID
ZDB-GENE-140106-206
Name
adhesion G protein-coupled receptor G2a
Symbol
adgrg2a Nomenclature History
Previous Names
  • gpr64
  • gpr64a
  • zmp:0000001246 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in male reproductive system disease. Is expressed in several structures, including eye; heart; integument; muscle; and pleuroperitoneal region. Orthologous to human ADGRG2 (adhesion G protein-coupled receptor G2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Harty et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adgrg2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked congenital bilateral absence of vas deferens Alliance Congenital bilateral absence of vas deferens, X-linked 300985
Associated With adgrg2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000203 GPS motif
Conserved_site IPR017983 GPCR, family 2, secretin-like, conserved site
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Domain IPR017981 GPCR, family 2-like, 7TM
Family IPR000832 GPCR, family 2, secretin-like
Homologous_superfamily IPR046338 GAIN domain superfamily
Domain Details Per Protein
Protein Length GAIN domain superfamily GPCR, family 2-like, 7TM GPCR, family 2, secretin-like GPCR, family 2, secretin-like, conserved site GPCR, rhodopsin-like, 7TM GPS motif
UniProtKB:E7F4F2 947
UniProtKB:A0A8M2B9R8 2289
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations