Gene

pde4a

ID
ZDB-GENE-131125-7
Name
phosphodiesterase 4A, cAMP-specific
Symbol
pde4a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in signal transduction. Predicted to localize to cytosol and perinuclear region of cytoplasm. Is expressed in oocyte and oocyte stage V. Orthologous to human PDE4A (phosphodiesterase 4A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Pang et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pde4a Human Ortholog
No data available
Associated With pde4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved site
Domain IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Domain IPR003607 HD/PDEase domain
Domain IPR040844 Phosphodiesterase 4 upstream conserved regions (UCR)
Family IPR023088 3'5'-cyclic nucleotide phosphodiesterase
Homologous_superfamily IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
Domain Details Per Protein
Protein Length 3'5'-cyclic nucleotide phosphodiesterase 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily 3'5'-cyclic nucleotide phosphodiesterase, conserved site HD/PDEase domain Phosphodiesterase 4 upstream conserved regions (UCR)
UniProtKB:A0A8M2BBS8 611
UniProtKB:E7FAS0 777
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pde4a-201 (1) Ensembl 5,068 nt
mRNA pde4a-202 (1) Ensembl 5,830 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations