Gene
acvr1bb
- ID
- ZDB-GENE-131120-9
- Name
- activin A receptor type 1Bb
- Symbol
- acvr1bb Nomenclature History
- Previous Names
-
- sb:eu632
- si:zfos-824d4.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have activin binding activity and activin receptor activity, type I. Predicted to be involved in several processes, including activin receptor signaling pathway; cellular response to growth factor stimulus; and protein phosphorylation. Predicted to localize to activin receptor complex. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ACVR1B (activin A receptor type 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu632 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pancreatic carcinoma | Alliance | Pancreatic cancer, somatic | 260350 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000472 | Activin types I and II receptor domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR003605 | GS domain |
| Family | IPR000333 | Ser/Thr protein kinase, TGFB receptor |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR045860 | Snake toxin-like superfamily |
Domain Details Per Protein
| Protein | Length | Activin types I and II receptor domain | GS domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Ser/Thr protein kinase, TGFB receptor | Snake toxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QZF0
|
498 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
acvr1bb-201
(1)
|
Ensembl | 1,789 nt | ||
| mRNA |
acvr1bb-202
(1)
|
Ensembl | 446 nt | ||
| mRNA |
acvr1bb-203
(1)
|
Ensembl | 1,502 nt |
Interactions and Pathways
No data available
Plasmids
No data available