Gene
adgra3
- ID
- ZDB-GENE-131003-2
- Name
- adhesion G protein-coupled receptor A3
- Symbol
- adgra3 Nomenclature History
- Previous Names
-
- gpr125
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Acts upstream of or within convergent extension involved in gastrulation; motor neuron migration; and regulation of establishment of planar polarity. Located in plasma membrane. Is expressed in several structures, including brain; liver; otic vesicle; pectoral fin; and pleuroperitoneal region. Orthologous to human ADGRA3 (adhesion G protein-coupled receptor A3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa21149 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa25377 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa34240 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa34241 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 4 of 4
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Adhesion G protein-coupled receptor A | Cysteine-rich flanking region, C-terminal | GAIN domain superfamily | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPS motif | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QX89
|
|||||||||||||||||
UniProtKB:S4X0Q8
|
1346 |
1 - 2 of 2
- Genome Browsers
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
adgra3-201
(1)
|
Ensembl | 2,184 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
No data available
- Comparative Orthology
- Alliance