Gene
dhx32b
- ID
- ZDB-GENE-130613-5
- Name
- DEAH (Asp-Glu-Ala-His) box polypeptide 32b
- Symbol
- dhx32b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Acts upstream of or within lens development in camera-type eye. Predicted to be part of spliceosomal complex. Orthologous to human DHX32 (DEAH-box helicase 32 (putative)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chiang et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR007502 | Helicase-associated domain |
| Domain | IPR011709 | DEAD-box helicase, OB fold |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR048333 | Helicase associated domain (HA2), winged-helix domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
1 - 5 of 5
Domain Details Per Protein
| Protein | Length | DEAD-box helicase, OB fold | Helicase-associated domain | Helicase associated domain (HA2), winged-helix domain | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|
|
UniProtKB:X1WHV8
|
729 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dhx32b-201
(1)
|
Ensembl | 3,289 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-139D20 | ZFIN Curated Data |
1 - 1 of 1
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_682226 (1) | 3280 nt | ||
| Genomic | GenBank:BX927337 (2) | 113790 nt | ||
| Polypeptide | UniProtKB:X1WHV8 (1) | 729 aa |
- Comparative Orthology
- Alliance
- Chiang, C.Y., Ching, Y.H., Chang, T.Y., Hu, L.S., Yong, Y.S., Keak, P.Y., Mustika, I., Lin, M.D., Liao, B.Y. (2019) Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome. Computational and structural biotechnology journal. 18:73-82
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Tokumasu, Y., Iida, A., Wang, Z., Ansai, S., Kinoshita, M., Sehara-Fujisawa, A. (2016) ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage without developmental defects. Development, growth & differentiation. 58(4):409-421
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
1 - 4 of 4
Show