Gene

gucy1b2

ID

ZDB-GENE-130530-664

Name

guanylate cyclase 1, soluble, beta 2

Symbol

gucy1b2 Nomenclature History

Previous Names

zmp:0000000661 (1)

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have guanylate cyclase activity; heme binding activity; and nucleotide binding activity. Predicted to be involved in cGMP biosynthetic process and intracellular signal transduction. Is expressed in olfactory epithelium and olfactory receptor cell.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Saraiva et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gucy1b2 Human Ortholog

No data available

Associated With gucy1b2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018297	Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase
Domain	IPR011644	Heme NO-binding
Domain	IPR011645	Haem NO binding associated
Homologous_superfamily	IPR024096	NO signalling/Golgi transport ligand-binding domain superfamily
Homologous_superfamily	IPR029787	Nucleotide cyclase
Homologous_superfamily	IPR038158	H-NOX domain superfamily
Homologous_superfamily	IPR042463	Haem NO binding associated domain superfamily

Domain Details Per Protein

Protein	Length	Adenylyl cyclase class-3/4/guanylyl cyclase	Adenylyl cyclase class-4/guanylyl cyclase, conserved site	Haem NO binding associated	Haem NO binding associated domain superfamily	Heme NO-binding	H-NOX domain superfamily	NO signalling/Golgi transport ligand-binding domain superfamily	Nucleotide cyclase
UniProtKB:E7F6T1 InterPro	757

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	gucy1b2-201 (1) Ensembl	Ensembl		2,343 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations