Gene

fat1b

ID

ZDB-GENE-130530-563

Name

FAT atypical cadherin 1b

Symbol

fat1b Nomenclature History

Previous Names

zmp:0000000560 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in posterior lateral line neuromast. Orthologous to human FAT1 (FAT atypical cadherin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Charlton-Perkins et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fat1b Human Ortholog

No data available

Associated With fat1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Conserved_site	IPR020894	Cadherin conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002126	Cadherin-like
Domain	IPR049883	NOTCH1 EGF-like calcium-binding domain
Family	IPR039808	Cadherin
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR015919	Cadherin-like superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site

Domain Details Per Protein

Protein	Length	Cadherin	Cadherin conserved site	Cadherin-like	Cadherin-like superfamily	Concanavalin A-like lectin/glucanase domain superfamily	EGF-like calcium-binding, conserved site	EGF-like calcium-binding domain	EGF-like domain	EGF-type aspartate/asparagine hydroxylation site	Laminin G domain	NOTCH1 EGF-like calcium-binding domain
UniProtKB:A0A8M9PBP8 InterPro	4503
UniProtKB:A0A140LGD3 InterPro	4481

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fat1b-201 (1) Ensembl	Ensembl	16,598 nt	Select Tool ZFIN BLAST
mRNA	fat1b-202 (1) Ensembl	Ensembl	16,650 nt	Select Tool ZFIN BLAST
mRNA	fat1b-203 (1) Ensembl	Ensembl	16,448 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations