Gene
cacna1ha
- ID
- ZDB-GENE-130103-1
- Name
- calcium channel, voltage-dependent, T type, alpha 1H subunit a
- Symbol
- cacna1ha Nomenclature History
- Previous Names
-
- sb:cb648
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have low voltage-gated calcium channel activity and voltage-gated sodium channel activity. Predicted to be involved in several processes, including calcium ion import; neuronal action potential; and positive regulation of calcium ion-dependent exocytosis. Predicted to localize to neuron projection and voltage-gated sodium channel complex. Human ortholog(s) of this gene implicated in childhood absence epilepsy and primary hyperaldosteronism. Is expressed in adaxial cell; diencephalon; heart; and retinal neural layer. Orthologous to human CACNA1H (calcium voltage-gated channel subunit alpha1 H).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb648 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR005821 | Ion transport domain |
Family | IPR002077 | Voltage-dependent calcium channel, alpha-1 subunit |
Family | IPR005445 | Voltage-dependent calcium channel, T-type, alpha-1 subunit |
Family | IPR043203 | Voltage-gated cation channel calcium and sodium |
Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
Domain Details Per Protein
Protein | Length | Ion transport domain | Voltage-dependent calcium channel, alpha-1 subunit | Voltage-dependent calcium channel, T-type, alpha-1 subunit | Voltage-dependent channel domain superfamily | Voltage-gated cation channel calcium and sodium |
---|---|---|---|---|---|---|
UniProtKB:A0A8M9PGJ8
|
2090 | |||||
UniProtKB:A0A8M3B162
|
2190 | |||||
UniProtKB:A0A8M9Q5I3
|
2198 | |||||
UniProtKB:A0A8M3AR36
|
2191 | |||||
UniProtKB:A0A8M3AY82
|
2180 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
antisense |
ottdart00000053725
(1)
|
Havana | 606 nt | |
mRNA |
cacna1ha-201
(1)
|
Havana | 7875 nt | |
mRNA |
cacna1ha-202
(1)
|
Ensembl | 1104 nt | |
mRNA |
cacna1ha-203
(1)
|
Ensembl | 2058 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance