Gene
ifit11
- ID
- ZDB-GENE-121214-302
- Name
- interferon-induced protein with tetratricopeptide repeats 11
- Symbol
- ifit11 Nomenclature History
- Previous Names
-
- Ifit12c (2)
- si:dkey-26g8.10
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to be involved in defense response to virus. Predicted to be active in cytosol. Is expressed in several structures, including caudal fin; gill; liver; muscle; and pleuroperitoneal region. Orthologous to several human genes including IFIT1 (interferon induced protein with tetratricopeptide repeats 1); IFIT1B (interferon induced protein with tetratricopeptide repeats 1B); and IFIT2 (interferon induced protein with tetratricopeptide repeats 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Varela et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat |
|---|---|---|---|
|
UniProtKB:A0A8M2BHB7
|
481 | ||
|
UniProtKB:E7FCM5
|
483 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ifit11-201
(1)
|
Ensembl | 2,412 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-26G8 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001190464 (1) | |||
| Genomic | GenBank:BX000534 (1) | 199670 nt | ||
| Polypeptide | UniProtKB:E7FCM5 (1) | 483 aa |
No data available
- Boskovic, S., Marín-Juez, R., Jasnic, J., Reischauer, S., El Sammak, H., Kojic, A., Faulkner, G., Radojkovic, D., Stainier, D.Y.R., Kojic, S. (2018) Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise. PLoS One. 13:e0204312
- Díaz-Pascual, F., Ortíz-Severín, J., Varas, M.A., Allende, M.L., Chávez, F.P. (2017) In vivo Host-Pathogen Interaction as Revealed by Global Proteomic Profiling of Zebrafish Larvae.. Frontiers in cellular and infection microbiology. 7:334
- Pereiro, P., Forn-Cuní, G., Dios, S., Coll, J., Figueras, A., Novoa, B. (2017) Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish. Antiviral Research. 145:146-159
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
- Varela, M., Diaz-Rosales, P., Pereiro, P., Forn-Cuní, G., Costa, M.M., Dios, S., Romero, A., Figueras, A., Novoa, B. (2014) Interferon-Induced Genes of the Expanded IFIT Family Show Conserved Antiviral Activities in Non-Mammalian Species. PLoS One. 9:e100015
- Liu, Y., Zhang, Y.B., Liu, T.K., and Gui, J.F. (2013) Lineage-Specific Expansion of IFIT Gene Family: An Insight into Coevolution with IFN Gene Family. PLoS One. 8(6):e66859
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