Gene
ptgfr
- ID
- ZDB-GENE-120919-6
- Name
- prostaglandin F receptor (FP)
- Symbol
- ptgfr Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Enables prostaglandin F receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; inflammatory response; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including gill; heart; liver; muscle; and pleuroperitoneal region. Orthologous to human PTGFR (prostaglandin F receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Prostanoid receptor | Thromboxane receptor |
|---|---|---|---|---|---|
|
UniProtKB:D7R7W5
|
390 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-214D11 | ZFIN Curated Data | |
| Contained in | BAC | CH211-270L17 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001185071 (1) | 1182 nt | ||
| Genomic | GenBank:CR762408 (2) | 153441 nt | ||
| Polypeptide | UniProtKB:D7R7W5 (1) | 390 aa |
- Tian, J., Du, Y., Yu, E., Lei, C., Xia, Y., Jiang, P., Li, H., Zhang, K., Li, Z., Gong, W., Xie, J., Wang, G. (2022) Prostaglandin 2α Promotes Autophagy and Mitochondrial Energy Production in Fish Hepatocytes. Cells. 11(12)
- Baker, S.J.C., Van Der Kraak, G. (2019) Investigating the role of prostaglandin receptor isoform EP4b in zebrafish ovulation. General and comparative endocrinology. 283:113228
- Iwasaki, R., Tsuge, K., Morimoto, K., Inazumi, T., Kawahara, O., Kawahara, A., Tsuchiya, S., and Sugimoto, Y. (2013) Molecular and pharmacological characterization of zebrafish 'contractile' and 'inhibitory' prostanoid receptors. Biochemical and Biophysical Research Communications. 438(2):353-8
- Kwok, A.H., Wang, Y., and Leung, F.C. (2012) Molecular characterization of prostaglandin F receptor (FP) and E receptor subtype 1 (EP(1)) in zebrafish. General and comparative endocrinology. 178(2):216-226
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