Gene
bsnb
- ID
- ZDB-GENE-120628-1
- Name
- bassoon (presynaptic cytomatrix protein) b
- Symbol
- bsnb Nomenclature History
- Previous Names
-
- zmp:0000001201
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to act upstream of or within synapse assembly. Predicted to be located in cell projection and presynaptic active zone. Is expressed in brain and forebrain. Orthologous to human BSN (bassoon presynaptic cytomatrix protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa6219 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa7352 | Allele with one point mutation | Unknown | Missense | ENU | |
| sa16951 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa21960 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa21961 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa21962 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41893 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41894 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41895 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41896 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 10 of 11
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Presynaptic Scaffold Protein Bassoon/Piccolo | Zinc finger, FYVE/PHD-type | Zinc finger, piccolo-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B2S6
|
3739 | ||||
|
UniProtKB:F1QTK1
|
3305 |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-295N8 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-61O18 | ZFIN Curated Data | |
| Contained in | Fosmid | CH1073-21L24 | ZFIN Curated Data |
1 - 3 of 3
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005155903 (1) | 14424 nt | ||
| Genomic | GenBank:CR847984 (2) | 78361 nt | ||
| Polypeptide | UniProtKB:A0A8M2B2S6 (1) | 3739 aa |
- Comparative Orthology
- Alliance
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Mouse | Bsn | 9 | Amino acid sequence comparison (1) |
- Hsu, P.J., Wang, H.D., Tseng, Y.C., Pan, S.W., Sampurna, B.P., Jong, Y.J., Yuh, C.H. (2021) L-Carnitine ameliorates congenital myopathy in a tropomyosin 3 de novo mutation transgenic zebrafish. Journal of Biomedical Science. 28:8
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Nonet, M.L. (2012) A Window into Domain Amplification Through Piccolo in Teleost Fish. G3 (Bethesda). 2(11):1325-1339
1 - 5 of 5
Show