Gene

ube2d2

ID
ZDB-GENE-120312-1
Name
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
Symbol
ube2d2 Nomenclature History
Previous Names
  • zgc:55886
  • zgc:77149
  • zmp:0000000618 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in negative regulation of smoothened signaling pathway. Predicted to localize to ubiquitin ligase complex. Orthologous to several human genes including UBE2D2 (ubiquitin conjugating enzyme E2 D2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Pan et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ube2d2 Human Ortholog
No data available
Associated With ube2d2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR023313 Ubiquitin-conjugating enzyme, active site
Domain IPR000608 Ubiquitin-conjugating enzyme E2
Homologous_superfamily IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Domain Details Per Protein
Protein Length Ubiquitin-conjugating enzyme, active site Ubiquitin-conjugating enzyme E2 Ubiquitin-conjugating enzyme/RWD-like
UniProtKB:Q7ZUK1 147
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ube2d2-201 (1) Ensembl 1,992 nt
mRNA ube2d2-202 (1) Ensembl 1,246 nt
mRNA ube2d2-203 (1) Ensembl 450 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations