Gene

mapkbp1

ID

ZDB-GENE-120207-1

Name

mitogen-activated protein kinase binding protein 1

Symbol

mapkbp1 Nomenclature History

Previous Names

si:dkey-89f23.3

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in nephronophthisis 20. Is expressed in brain; head; and somite. Orthologous to human MAPKBP1 (mitogen-activated protein kinase binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Macia et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mapkbp1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nephronophthisis 20	Alliance	Nephronophthisis 20	617271

Associated With mapkbp1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR024977	Anaphase-promoting complex subunit 4-like, WD40 domain
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Anaphase-promoting complex subunit 4-like, WD40 domain	Quinoprotein alcohol dehydrogenase-like superfamily	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M9PL31 InterPro	1574
UniProtKB:A0A0R4ICM6 InterPro	1578
UniProtKB:A0A8M9P0C8 InterPro	1572

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mapkbp1-201 (1) Ensembl	Ensembl	1,347 nt	Select Tool
mRNA	mapkbp1-202 (1) Ensembl	Ensembl	5,155 nt	Select Tool ZFIN BLAST
mRNA	mapkbp1-203 (1) Ensembl	Ensembl	5,245 nt	Select Tool ZFIN BLAST
mRNA	mapkbp1-204 (1) Ensembl	Ensembl	5,263 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations