Gene
fat2
- ID
- ZDB-GENE-111031-1
- Name
- FAT atypical cadherin 2
- Symbol
- fat2 Nomenclature History
- Previous Names
-
- fk09f07
- wu:fk09f07
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to localize to adherens junction. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 45. Is expressed in cerebellum; granule cell; hindbrain; and optic tectum. Orthologous to human FAT2 (FAT atypical cadherin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Takeuchi et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spinocerebellar ataxia 45 | Alliance | Spinocerebellar ataxia 45 | 617769 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020894 | Cadherin conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR002126 | Cadherin-like |
| Family | IPR039808 | Cadherin |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR015919 | Cadherin-like superfamily |
Domain Details Per Protein
| Protein | Length | Cadherin | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like domain | Laminin G domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FB42
|
4342 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance