Gene
ndst1a
- ID
- ZDB-GENE-111012-2
- Name
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
- Symbol
- ndst1a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have [heparan sulfate]-glucosamine N-sulfotransferase activity and hydrolase activity. Involved in cranial skeletal system development. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in head; optic tectum; and pectoral fin. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Filipek-Górniok et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Filipek-Górniok et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 46 | Alliance | Intellectual developmental disorder, autosomal recessive 46 | 616116 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulfate sulfotransferase | Heparan sulphate-N-deacetylase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|
|
UniProtKB:E7F0G2
|
869 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndst1a-201
(1)
|
Ensembl | 7,532 nt | ||
| mRNA |
ndst1a-202
(1)
|
Ensembl | 8,357 nt | ||
| mRNA |
ndst1a-203
(1)
|
Ensembl | 8,270 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance