Gene

spred2a

ID
ZDB-GENE-110830-2
Name
sprouty related EVH1 domain containing 2a
Symbol
spred2a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have protein kinase binding activity. Predicted to be involved in positive regulation of DNA damage response, signal transduction by p53 class mediator and regulation of protein modification process. Predicted to localize to membrane. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spred2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Noonan syndrome 14 619745
Associated With spred2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000697 WH1/EVH1 domain
Domain IPR023337 c-Kit-binding domain
Domain IPR041937 SPRE, EVH1 domain
Family IPR007875 Sprouty
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length c-Kit-binding domain PH-like domain superfamily SPRE, EVH1 domain Sprouty WH1/EVH1 domain
UniProtKB:A0A8N7T5I8 427
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA spred2a-201 (1) Ensembl 1,245 nt
mRNA spred2a-203 (1) Ensembl 6,700 nt
ncRNA spred2a-002 (1) Ensembl 542 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations