Gene
tbx19
- ID
- ZDB-GENE-110411-5
- Name
- T-box transcription factor 19
- Symbol
- tbx19 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II activating transcription factor binding activity; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including mesoderm formation; regulation of transcription by RNA polymerase II; and somitogenesis. Predicted to localize to nuclear chromatin. Human ortholog(s) of this gene implicated in adrenocorticotropic hormone deficiency and inherited metabolic disorder. Is expressed in diencephalon; pars anterior; and rostral pars anterior. Orthologous to human TBX19 (T-box transcription factor 19).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| adrenocorticotropic hormone deficiency | Alliance | Adrenocorticotropic hormone deficiency | 201400 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018186 | Transcription factor, T-box, conserved site |
| Domain | IPR046360 | T-box transcription factor, DNA-binding domain |
| Family | IPR001699 | T-box transcription factor |
| Family | IPR002070 | Transcription factor, Brachyury |
| Homologous_superfamily | IPR008967 | p53-like transcription factor, DNA-binding domain superfamily |
| Homologous_superfamily | IPR036960 | T-box superfamily |
Domain Details Per Protein
| Protein | Length | p53-like transcription factor, DNA-binding domain superfamily | T-box superfamily | T-box transcription factor | T-box transcription factor, DNA-binding domain | Transcription factor, Brachyury | Transcription factor, T-box, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RSL4
|
436 | ||||||
|
UniProtKB:A0A8M9Q8V0
|
230 |
Interactions and Pathways
No data available
Plasmids
No data available