Gene

oat

ID
ZDB-GENE-110411-148
Name
ornithine aminotransferase
Symbol
oat Nomenclature History
Previous Names
  • si:dkey-68e16.4
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have ornithine-oxo-acid transaminase activity and pyridoxal phosphate binding activity. Predicted to be involved in arginine catabolic process to glutamate and arginine catabolic process to proline via ornithine. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in gyrate atrophy. Orthologous to human OAT (ornithine aminotransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zielonka et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With oat Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
gyrate atrophy Alliance Gyrate atrophy of choroid and retina with or without ornithinemia 258870
Associated With oat Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR049704 Aminotransferases class-III pyridoxal-phosphate attachment site
Family IPR005814 Aminotransferase class-III
Family IPR010164 Ornithine aminotransferase
Family IPR050103 Class-III Pyridoxal-phosphate-dependent Aminotransferase
Homologous_superfamily IPR015421 Pyridoxal phosphate-dependent transferase, major domain
Homologous_superfamily IPR015422 Pyridoxal phosphate-dependent transferase, small domain
Homologous_superfamily IPR015424 Pyridoxal phosphate-dependent transferase
Domain Details Per Protein
Protein Length Aminotransferase class-III Aminotransferases class-III pyridoxal-phosphate attachment site Class-III Pyridoxal-phosphate-dependent Aminotransferase Ornithine aminotransferase Pyridoxal phosphate-dependent transferase Pyridoxal phosphate-dependent transferase, major domain Pyridoxal phosphate-dependent transferase, small domain
UniProtKB:F8W5L3 444
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA oat-201 (1) Ensembl 4,912 nt
mRNA oat-202 (1) Ensembl 1,830 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations