Gene
oat
- ID
- ZDB-GENE-110411-148
- Name
- ornithine aminotransferase
- Symbol
- oat Nomenclature History
- Previous Names
-
- si:dkey-68e16.4
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have ornithine-oxo-acid transaminase activity and pyridoxal phosphate binding activity. Predicted to be involved in arginine catabolic process to glutamate and arginine catabolic process to proline via ornithine. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in gyrate atrophy. Orthologous to human OAT (ornithine aminotransferase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Zielonka et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
gyrate atrophy | Alliance | Gyrate atrophy of choroid and retina with or without ornithinemia | 258870 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR049704 | Aminotransferases class-III pyridoxal-phosphate attachment site |
Family | IPR005814 | Aminotransferase class-III |
Family | IPR010164 | Ornithine aminotransferase |
Family | IPR050103 | Class-III Pyridoxal-phosphate-dependent Aminotransferase |
Homologous_superfamily | IPR015421 | Pyridoxal phosphate-dependent transferase, major domain |
Homologous_superfamily | IPR015422 | Pyridoxal phosphate-dependent transferase, small domain |
Homologous_superfamily | IPR015424 | Pyridoxal phosphate-dependent transferase |
Domain Details Per Protein
Protein | Length | Aminotransferase class-III | Aminotransferases class-III pyridoxal-phosphate attachment site | Class-III Pyridoxal-phosphate-dependent Aminotransferase | Ornithine aminotransferase | Pyridoxal phosphate-dependent transferase | Pyridoxal phosphate-dependent transferase, major domain | Pyridoxal phosphate-dependent transferase, small domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:F8W5L3
|
444 |
Interactions and Pathways
No data available
Plasmids
No data available