Gene
znfl1b
- ID
- ZDB-GENE-110131-6
- Name
- zinc finger-like gene 1b
- Symbol
- znfl1b Nomenclature History
- Previous Names
-
- znfl1d (1)
- si:dkey-103d23.5
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable nucleic acid binding activity and zinc ion binding activity. Acts upstream of or within hindbrain development. Is expressed in mesoderm and neuroectoderm.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa12883 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa38729 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41382 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41383 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger, CCHC-type | Zinc finger, CCHC-type superfamily |
|---|---|---|---|
|
UniProtKB:F6P4J7
|
505 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
znfl1b-201
(1)
|
Ensembl | 3,365 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-14O1 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-103D23 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001113633 (1) | 3365 nt | ||
| Genomic | GenBank:BX571786 (1) | 180164 nt | ||
| Polypeptide | UniProtKB:F6P4J7 (1) | 505 aa |
- Comparative Orthology
- Alliance
No data available
- Li, J., Gao, F., Zhao, Y., He, L., Huang, Y., Yang, X., Zhou, Y., Yu, L., Zhao, Q., Dong, X. (2018) Zebrafish znfl1s regulate left-right asymmetry patterning through controlling the expression of fgfr1a. Journal of Cellular Physiology. 234(3):1987-1995
- Li, J., Zhao, Y., He, L., Huang, Y., Yang, X., Yu, L., Zhao, Q., Dong, X. (2018) Znfl1s are essential for patterning the anterior-posterior axis of zebrafish posterior hindbrain by acting as direct target genes of retinoic acid. Mechanisms of Development. 155:27-33
- Dong, X., Li, J., He, L., Gu, C., Jia, W., Yue, Y., Li, J., Zhang, Q., Chu, L., Zhao, Q. (2017) Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes.. The Journal of biological chemistry. 292(31):13045-13055
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