Gene

ptprb

ID

ZDB-GENE-101108-3

Name

protein tyrosine phosphatase receptor type b

Symbol

ptprb Nomenclature History

Previous Names

zve-ptp (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Involved in blood vessel development. Predicted to localize to integral component of membrane. Is expressed in oocyte and vasculature. Orthologous to human PTPRB (protein tyrosine phosphatase receptor type B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Carra et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprb Human Ortholog

No data available

Associated With ptprb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR003961	Fibronectin type III
Domain	IPR041201	PTPRJ, transmembrane domain
Family	IPR050713	Receptor-type Tyrosine-protein Phosphatases/Ushers
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR036116	Fibronectin type III superfamily