Gene
lipeb
- ID
- ZDB-GENE-100921-71
- Name
- lipase, hormone-sensitive b
- Symbol
- lipeb Nomenclature History
- Previous Names
-
- si:ch211-194b7.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have hormone-sensitive lipase activity and lipase activity. Predicted to be involved in cholesterol metabolic process and triglyceride catabolic process. Predicted to localize to caveola and cytosol. Human ortholog(s) of this gene implicated in arteriosclerosis; familial partial lipodystrophy type 6; and hypertension. Orthologous to human LIPE (lipase E, hormone sensitive type).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
familial partial lipodystrophy type 6 | Alliance | Lipodystrophy, familial partial, type 6 | 615980 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR002168 | Lipase, GDXG, putative histidine active site |
Active_site | IPR033140 | Lipase, GDXG, putative serine active site |
Domain | IPR010468 | Hormone-sensitive lipase, N-terminal |
Domain | IPR013094 | Alpha/beta hydrolase fold-3 |
Homologous_superfamily | IPR029058 | Alpha/Beta hydrolase fold |
Domain Details Per Protein
Protein | Length | Alpha/Beta hydrolase fold | Alpha/beta hydrolase fold-3 | Hormone-sensitive lipase, N-terminal | Lipase, GDXG, putative histidine active site | Lipase, GDXG, putative serine active site |
---|---|---|---|---|---|---|
UniProtKB:A0A8M3AI41
|
881 | |||||
UniProtKB:A0A8M3ATG0
|
894 | |||||
UniProtKB:A0A8M3AJ48
|
895 | |||||
UniProtKB:A0A8M3B1P6
|
857 | |||||
UniProtKB:A0A8M3AQL5
|
886 | |||||
UniProtKB:A0A8M3AJ52
|
851 |
Interactions and Pathways
No data available
Plasmids
No data available