Gene
cyp17a2
- ID
- ZDB-GENE-100822-1
- Name
- cytochrome P450, family 17, subfamily A, polypeptide 2
- Symbol
- cyp17a2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Enables steroid 17-alpha-monooxygenase activity. Acts upstream of or within progesterone metabolic process. Is expressed in brain and endocrine system. Human ortholog(s) of this gene implicated in several diseases, including cholelithiasis; congenital adrenal hyperplasia; gallbladder cancer; osteoporosis; and prostate cancer. Orthologous to human CYP17A1 (cytochrome P450 family 17 subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A7U483
|
495 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp17a2-201
(1)
|
Ensembl | 1,488 nt | ||
| ncRNA |
cyp17a2-002
(1)
|
Ensembl | 341 nt |
Interactions and Pathways
No data available
Plasmids
No data available