Gene

maml1

ID
ZDB-GENE-100820-2
Name
mastermind-like transcriptional coactivator 1
Symbol
maml1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have transcription coactivator activity. Predicted to be involved in Notch signaling pathway and positive regulation of transcription by RNA polymerase II. Predicted to localize to nuclear speck. Is expressed in telencephalon. Orthologous to human MAML1 (mastermind like transcriptional coactivator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chapouton et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With maml1 Human Ortholog
No data available
Associated With maml1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR019082 Neurogenic mastermind-like, N-terminal
Domain IPR048455 Mastermind-like 1/3, transactivation domain 2
Domain IPR048456 Mastermind-like 1/3, transactivation domain 1
Family IPR046369 Mastermind-like 1-3
Homologous_superfamily IPR046370 Neurogenic mastermind-like, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Mastermind-like 1-3 Mastermind-like 1/3, transactivation domain 1 Mastermind-like 1/3, transactivation domain 2 Neurogenic mastermind-like, N-terminal Neurogenic mastermind-like, N-terminal domain superfamily
UniProtKB:A0A0R4IKI2 1049
UniProtKB:A0A8N7TF91 1048
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA maml1-201 (1) Ensembl 5,478 nt
mRNA maml1-202 (1) Ensembl 3,150 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations