Gene
itgb6
- ID
- ZDB-GENE-100812-2
- Name
- integrin, beta 6
- Symbol
- itgb6 Nomenclature History
- Previous Names
-
- im:7165241
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to localize to cell surface; focal adhesion; and integrin complex. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1H. Is expressed in several structures, including adaxial cell; liver; musculature system; otic vesicle; and sensory system. Orthologous to human ITGB6 (integrin subunit beta 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7165241 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| amelogenesis imperfecta type 1H | Alliance | Amelogenesis imperfecta, type IH | 616221 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002369 | Integrin beta subunit, VWA domain |
| Domain | IPR012896 | Integrin beta subunit, tail |
| Domain | IPR013111 | EGF-like domain, extracellular |
| Domain | IPR014836 | Integrin beta subunit, cytoplasmic domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR033760 | Integrin beta N-terminal |
| Domain | IPR040622 | Integrin beta, epidermal growth factor-like domain 1 |
| Family | IPR015812 | Integrin beta subunit |
| Homologous_superfamily | IPR032695 | Integrin domain superfamily |
| Homologous_superfamily | IPR036349 | Integrin beta tail domain superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
| Protein | Length | EGF-like domain, extracellular | Integrin beta, epidermal growth factor-like domain 1 | Integrin beta N-terminal | Integrin beta subunit | Integrin beta subunit, cytoplasmic domain | Integrin beta subunit, tail | Integrin beta subunit, VWA domain | Integrin beta tail domain superfamily | Integrin domain superfamily | PSI domain | von Willebrand factor A-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QGX0
|
782 |
Interactions and Pathways
No data available
Plasmids
No data available