Gene
afap1l2
- ID
- ZDB-GENE-100318-1
- Name
- actin filament associated protein 1-like 2
- Symbol
- afap1l2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable SH2 domain binding activity and SH3 domain binding activity. Acts upstream of or within closure of optic fissure. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in diencephalon; forebrain; optic cup; optic furrow; and optic stalk. Orthologous to human AFAP1L2 (actin filament associated protein 1 like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Cao et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Cao et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-filament associated protein | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PX59
|
886 | |||
|
UniProtKB:A0A8M9Q402
|
890 | |||
|
UniProtKB:A0A8M9PAX9
|
889 | |||
|
UniProtKB:A0A8M9PTK4
|
862 | |||
|
UniProtKB:E7FH23
|
859 | |||
|
UniProtKB:A0A8M3B4R4
|
858 | |||
|
UniProtKB:A0A8M9Q0R8
|
889 | |||
|
UniProtKB:A0A8M9Q407
|
861 | |||
|
UniProtKB:A0A8M9QN06
|
887 | |||
|
UniProtKB:A0A8M9QJ86
|
886 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
afap1l2-201
(1)
|
Ensembl | 3,347 nt | ||
| mRNA |
afap1l2-202
(1)
|
Ensembl | 2,988 nt | ||
| mRNA |
afap1l2-203
(1)
|
Ensembl | 2,879 nt |
Interactions and Pathways
No data available
Plasmids
No data available