Gene
afap1l2
- ID
- ZDB-GENE-100318-1
- Name
- actin filament associated protein 1-like 2
- Symbol
- afap1l2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have SH2 domain binding activity and SH3 domain binding activity. Involved in closure of optic fissure. Predicted to localize to cytosol. Is expressed in diencephalon; forebrain; optic cup; optic furrow; and optic stalk. Orthologous to human AFAP1L2 (actin filament associated protein 1 like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Cao et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Cao et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-filament associated protein | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PX59
|
886 | |||
|
UniProtKB:A0A8M9Q402
|
890 | |||
|
UniProtKB:A0A8M9PAX9
|
889 | |||
|
UniProtKB:A0A8M9PTK4
|
862 | |||
|
UniProtKB:E7FH23
|
859 | |||
|
UniProtKB:A0A8M3B4R4
|
858 | |||
|
UniProtKB:A0A8M9Q0R8
|
889 | |||
|
UniProtKB:A0A8M9Q407
|
861 | |||
|
UniProtKB:A0A8M9QN06
|
887 | |||
|
UniProtKB:A0A8M9QJ86
|
886 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
afap1l2-201
(1)
|
Ensembl | 3,347 nt | ||
| mRNA |
afap1l2-202
(1)
|
Ensembl | 2,988 nt | ||
| mRNA |
afap1l2-203
(1)
|
Ensembl | 2,879 nt |
Interactions and Pathways
No data available
Plasmids
No data available