Gene
eif3f
- ID
- ZDB-GENE-100215-2
- Name
- eukaryotic translation initiation factor 3, subunit F
- Symbol
- eif3f Nomenclature History
- Previous Names
-
- si:dkey-58j19.2
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to contribute to translation initiation factor activity. Involved in cranial skeletal system development. Predicted to localize to eukaryotic translation initiation factor 3 complex, eIF3m. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in female organism. Orthologous to human EIF3F (eukaryotic translation initiation factor 3 subunit F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Newman et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 67 | Alliance | Intellectual developmental disorder, autosomal recessive 67 | 618295 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EIF3F/CSN6-like, C-terminal | Eukaryotic translation initiation factor 3 subunit F | JAB1/MPN/MOV34 metalloenzyme domain | MPN domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M1NXK7
|
273 |
Interactions and Pathways
No data available
Plasmids
No data available