Gene
cpa6
- ID
- ZDB-GENE-091204-331
- Name
- carboxypeptidase A6
- Symbol
- cpa6 Nomenclature History
- Previous Names
-
- si:dkey-78n18.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Enables carboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in several structures, including head; pectoral fin; pectoral fin bud; segmental plate; and tail bud. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA6 (carboxypeptidase A6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lopes et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial febrile seizures 11 | Alliance | Febrile seizures, familial, 11 | 614418 |
| familial temporal lobe epilepsy 5 | Alliance | Epilepsy, familial temporal lobe, 5 | 614417 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Carboxypeptidase, activation peptide | Metallocarboxypeptidase-like, propeptide | Peptidase M14, carboxypeptidase A |
|---|---|---|---|---|
|
UniProtKB:A0A8M3AW04
|
377 | |||
|
UniProtKB:E7F2H8
|
442 | |||
|
UniProtKB:A0A8M9PUE3
|
189 |
Interactions and Pathways
No data available
Plasmids
No data available