Gene
cpa6
- ID
- ZDB-GENE-091204-331
- Name
- carboxypeptidase A6
- Symbol
- cpa6 Nomenclature History
- Previous Names
-
- si:dkey-78n18.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Exhibits carboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Is expressed in several structures, including head; pectoral fin; pectoral fin bud; segmental plate; and tail bud. Orthologous to human CPA6 (carboxypeptidase A6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lopes et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial febrile seizures 11 | Alliance | Febrile seizures, familial, 11 | 614418 |
| familial temporal lobe epilepsy 5 | Alliance | Epilepsy, familial temporal lobe, 5 | 614417 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Carboxypeptidase, activation peptide | Metallocarboxypeptidase-like, propeptide | Peptidase M14, carboxypeptidase A |
|---|---|---|---|---|
|
UniProtKB:A0A8M3AW04
|
377 | |||
|
UniProtKB:E7F2H8
|
442 | |||
|
UniProtKB:A0A8M9PUE3
|
189 |
Interactions and Pathways
No data available
Plasmids
No data available