Gene
adamts6
- ID
- ZDB-GENE-091113-9
- Name
- ADAM metallopeptidase with thrombospondin type 1 motif, 6
- Symbol
- adamts6 Nomenclature History
- Previous Names
-
- si:dkeyp-7g10.1
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and thymus. Orthologous to human ADAMTS6 (ADAM metallopeptidase with thrombospondin type 1 motif 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Brunet et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001590 | Peptidase M12B, ADAM/reprolysin |
| Domain | IPR002870 | Peptidase M12B, propeptide |
| Domain | IPR010294 | ADAMTS/ADAMTS-like, Spacer 1 |
| Domain | IPR010909 | PLAC |
| Domain | IPR041645 | ADAMTS, cysteine-rich domain 2 |
| Domain | IPR045371 | ADAMTS/ADAMTS-like, cysteine-rich domain 3 |
| Family | IPR013273 | ADAMTS/ADAMTS-like |
| Family | IPR050439 | ADAMTS and ADAMTS-like |
| Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
Domain Details Per Protein
| Protein | Length | ADAMTS/ADAMTS-like | ADAMTS/ADAMTS-like, cysteine-rich domain 3 | ADAMTS/ADAMTS-like, Spacer 1 | ADAMTS and ADAMTS-like | ADAMTS, cysteine-rich domain 2 | Metallopeptidase, catalytic domain superfamily | Peptidase M12B, ADAM/reprolysin | Peptidase M12B, propeptide | PLAC | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QGU5
|
588 | |||||||||||
|
UniProtKB:A0A8M6Z1D0
|
1116 | |||||||||||
|
UniProtKB:A0A8M9QKW4
|
644 | |||||||||||
|
UniProtKB:A0A8M3B350
|
627 | |||||||||||
|
UniProtKB:A0A8M9Q6C5
|
588 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adamts6-201
(1)
|
Ensembl | 3,351 nt |
Interactions and Pathways
No data available
Plasmids
No data available