Gene
smarcad1b
- ID
- ZDB-GENE-091113-61
- Name
- SNF2 related chromatin remodeling ATPase with DExD box 1b
- Symbol
- smarcad1b Nomenclature History
- Previous Names
-
- si:dkey-76p7.6
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity; DNA-dependent ATPase activity; and chromatin binding activity. Predicted to be involved in ATP-dependent chromatin remodeling and DNA double-strand break processing. Predicted to localize to nucleus and site of double-strand break. Human ortholog(s) of this gene implicated in adermatoglyphia. Orthologous to human SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| adermatoglyphia | Alliance | Adermatoglyphia | 136000 |
| BASAN syndrome | Alliance | Basan syndrome | 129200 |
| Huriez syndrome | 181600 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000330 | SNF2, N-terminal |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR003892 | Ubiquitin system component CUE |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR049730 | SNF2/RAD5-like, C-terminal helicase domain |
| Homologous_superfamily | IPR009060 | UBA-like superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | SNF2/RAD5-like, C-terminal helicase domain | UBA-like superfamily | Ubiquitin system component CUE |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F1C4
|
954 | ||||||||
|
UniProtKB:A0A8N7UVW1
|
809 | ||||||||
|
UniProtKB:A0A8M2B257
|
955 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
smarcad1b-201
(1)
|
Ensembl | 3,464 nt | ||
| ncRNA |
smarcad1b-002
(1)
|
Ensembl | 598 nt |
Interactions and Pathways
No data available
Plasmids
No data available