Gene
gnb4a
- ID
- ZDB-GENE-091102-1
- Name
- guanine nucleotide binding protein (G protein), beta polypeptide 4a
- Symbol
- gnb4a Nomenclature History
- Previous Names
-
- gnb4
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate F. Is expressed in head; neuromast; and posterior lateral line primordium. Orthologous to human GNB4 (G protein subunit beta 4).
- Genome Resources
-
- Alliance (1)
- Gene:100332205 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xu et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease dominant intermediate F | Alliance | Charcot-Marie-Tooth disease, dominant intermediate F | 615185 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR001632 | G-protein, beta subunit |
| Family | IPR016346 | Guanine nucleotide-binding protein, beta subunit |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein, beta subunit | G-protein beta WD-40 repeat | Guanine nucleotide-binding protein, beta subunit | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9NZA4
|
340 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance