Gene
cacng2b
- ID
- ZDB-GENE-090624-3
- Name
- calcium channel, voltage-dependent, gamma subunit 2b
- Symbol
- cacng2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to have voltage-gated calcium channel activity. Predicted to be involved in protein localization to organelle; regulation of AMPA receptor activity; and transmission of nerve impulse. Predicted to localize to AMPA glutamate receptor complex and postsynaptic density membrane. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 10. Is expressed in brain. Orthologous to human CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2).
- Genome Resources
-
- Alliance (1)
- Gene:569855 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Roy et al., 2016
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) Single Cell Expression Atlas (1) Daniocell (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Roy et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 10 | Alliance | ?Intellectual developmental disorder, autosomal dominant 10 | 614256 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PMP-22/EMP/MP20/Claudin | Voltage-dependent calcium channel gamma subunit | Voltage-dependent calcium channel, gamma subunit |
|---|---|---|---|---|
|
UniProtKB:A0A0R4INZ4
|
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance