Gene

terf1

ID

ZDB-GENE-090612-2

Name

telomeric repeat binding factor (NIMA-interacting) 1

Symbol

terf1 Nomenclature History

Previous Names

wu:fb74c04

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Exhibits telomeric DNA binding activity. Predicted to contribute to telomerase activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; positive regulation of microtubule polymerization; and telomere maintenance via telomerase. Predicted to localize to nuclear telomere cap complex. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Orthologous to human TERF1 (telomeric repeat binding factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Wagner et al., 2017

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With terf1 Human Ortholog

No data available

Associated With terf1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001005	SANT/Myb domain
Domain	IPR017930	Myb domain
Family	IPR017357	Telomeric repeat-binding factor 1/2
Family	IPR052450	Telomeric Repeat-Binding Domain-Containing Protein
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR036507	Telomere repeat-binding factor, dimerisation domain superfamily

Domain Details Per Protein

Protein	Length	Homedomain-like superfamily	Myb domain	SANT/Myb domain	Telomere repeat-binding factor, dimerisation domain superfamily	Telomeric Repeat-Binding Domain-Containing Protein	Telomeric repeat-binding factor 1/2
UniProtKB:A0A8N7TFE0 InterPro	379
UniProtKB:A0A8M9PXV3 InterPro	386

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	terf1-201 (1) Ensembl	Ensembl	1,543 nt	Select Tool
mRNA	terf1-202 (1) Ensembl	Ensembl	909 nt	Select Tool
mRNA	terf1-204 (1) Ensembl	Ensembl	2,900 nt	Select Tool ZFIN BLAST
ncRNA	terf1-003 (1) Ensembl	Ensembl	667 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations