Gene
cnga3a
- ID
- ZDB-GENE-090611-2
- Name
- cyclic nucleotide gated channel subunit alpha 3a
- Symbol
- cnga3a Nomenclature History
- Previous Names
-
- cnga3
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport and visual perception. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in achromatopsia 2 and color blindness. Is expressed in gonad; heart; and nervous system. Orthologous to human CNGA3 (cyclic nucleotide gated channel subunit alpha 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| achromatopsia 2 | Alliance | Achromatopsia 2 | 216900 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018488 | Cyclic nucleotide-binding, conserved site |
| Domain | IPR000595 | Cyclic nucleotide-binding domain |
| Domain | IPR005821 | Ion transport domain |
| Domain | IPR032406 | Cyclic nucleotide-gated channel, C-terminal leucine zipper domain |
| Family | IPR050866 | Cyclic nucleotide-gated cation channel |
| Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
| Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Cyclic nucleotide-binding, conserved site | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Cyclic nucleotide-gated cation channel | Cyclic nucleotide-gated channel, C-terminal leucine zipper domain | Ion transport domain | RmlC-like jelly roll fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PN18
|
706 | |||||||
|
UniProtKB:A0A8M3ATJ7
|
664 | |||||||
|
UniProtKB:A0A8M2BDH8
|
765 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cnga3a-201
(1)
|
Ensembl | 2,136 nt | ||
| mRNA |
cnga3a-202
(1)
|
Ensembl | 2,807 nt | ||
| mRNA |
cnga3a-203
(1)
|
Ensembl | 2,115 nt |
Interactions and Pathways
No data available
Plasmids
No data available