Gene
cnga3a
- ID
- ZDB-GENE-090611-2
- Name
- cyclic nucleotide gated channel subunit alpha 3a
- Symbol
- cnga3a Nomenclature History
- Previous Names
-
- cnga3
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport; response to stimulus; and visual perception. Predicted to localize to integral component of membrane. Is expressed in gonad; heart; and nervous system. Human ortholog(s) of this gene implicated in achromatopsia 2 and color blindness. Orthologous to human CNGA3 (cyclic nucleotide gated channel subunit alpha 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
achromatopsia 2 | Alliance | Achromatopsia 2 | 216900 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018488 | Cyclic nucleotide-binding, conserved site |
Domain | IPR000595 | Cyclic nucleotide-binding domain |
Domain | IPR005821 | Ion transport domain |
Domain | IPR032406 | Cyclic nucleotide-gated channel, C-terminal leucine zipper domain |
Family | IPR050866 | Cyclic nucleotide-gated cation channel |
Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Cyclic nucleotide-binding, conserved site | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Cyclic nucleotide-gated cation channel | Cyclic nucleotide-gated channel, C-terminal leucine zipper domain | Ion transport domain | RmlC-like jelly roll fold |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PN18
|
706 | |||||||
UniProtKB:A0A8M3ATJ7
|
664 | |||||||
UniProtKB:A0A8M2BDH8
|
765 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
cnga3a-201
(1)
|
Ensembl | 2136 nt | |
mRNA |
cnga3a-202
(1)
|
Havana | 2807 nt | |
mRNA |
cnga3a-203
(1)
|
Ensembl | 2115 nt |
Interactions and Pathways
No data available
Plasmids
No data available